The 17 Sustainable Development Goals (SDGs) included in the 2015-2030 Agenda refer to different areas of social, economic and environmental development, which need to be considered in an integrated approach, including international cooperation and the political and institutional context. Climate changes (Cop21, 2015) and Extreme events and disasters (Sendai Framework, 2015) are strictly connected.  Istat has a dual role: coordination of the provision of official statistics produced by the various institutional agencies belonging to the National Statistical System (Sistan) and responsibility in coordinating the national production of the SDG indicators. Therefore, the work of the inter-institutional discussion inside and outside the boundaries of Sistan is essential to complement a methodologically consistent mapping, integrated and shared, and an assessment of the overall availability of the SDG indicators. In this context, Istat is working  on a participatory platform to promote follow-up, sharing of information, development of necessary and fruitful synergies, in order to achieve the dissemination of indicators already available and then the development of those not yet available. In this context, indicators, methodologies, innovations are crucial to face with these challenges and could be considered from different point of views. Challenges are opportunities for fruitful improvement of the SDGs Italian system of indicators that makes progress in the last disseminations.