Open Conference Systems, 50th Scientific meeting of the Italian Statistical Society

Font Size: 
MATHEMATICAL MODELS FOR EMERGING AND RE-EMERGING MOSQUITO-BORNE DISEASES
Giorgio Guzzetta

Last modified: 2018-05-25

Abstract


Infections transmitted by mosquitoes represent an important burden to public health systems worldwide. “Classical†mosquito-borne diseases such as chikungunya and dengue are rapidly expanding their geographic range; Zika virus has emerged as a new pandemic threat with severe congenital syndromes; several other mosquito-borne viruses such as West Nile and Usutu viruses are under close surveillance because of their increasing spread in animal hosts and the fear of potential mutations causing severe symptomaticity and/or transmission in humans as well.
Mathematical and computational models can improve our basic knowledge on infection and outbreak dynamics, quantify potential transmission risks and support the planning and design of preventive and reactive interventions. We will showcase a number of practical applications of models to the vector population, behavior and ecology, allowing the estimation of potential transmission risks to humans and the cost-effectiveness of preventive interventions. We will then proceed to illustrate multiple examples concerning quantitative inferences on actual outbreak dynamics and control interventions for chikungunya, dengue and Zika, in different environmental and geographical settings.

References


* Guzzetta G, Poletti P, Montarsi F, Baldacchino F, Capelli G, Rizzoli A, Rosà R, Merler S. Assessing the potential risk of Zika virus epidemics in temperate areas with established Aedes albopictus populations. Eurosurveillance. 2016 Apr 14;21(15).* Guzzetta G, Montarsi F, Baldacchino FA, Metz M, Capelli G, Rizzoli A, Pugliese A, Rosà R, Poletti P, Merler S. Potential risk of dengue and chikungunya outbreaks in northern Italy based on a population model of Aedes albopictus (Diptera: Culicidae). PLoS neglected tropical diseases. 2016 Jun 15;10(6):e0004762.* Guzzetta G, Trentini F, Poletti P, Baldacchino FA, Montarsi F, Capelli G, Rizzoli A, Rosà R, Merler S, Melegaro A. Effectiveness and economic assessment of routine larviciding for prevention of chikungunya and dengue in temperate urban settings in Europe. PLoS neglected tropical diseases. 2017 Sep 11;11(9):e0005918.* Manica M, Guzzetta G, Poletti P, Filipponi F, Solimini A, Caputo B, Della Torre A, Rosà R, Merler S. Transmission dynamics of the ongoing chikungunya outbreak in Central Italy: from coastal areas to the metropolitan city of Rome, summer 2017. Eurosurveillance. 2017 Nov 2;22(44).* Marini G, Guzzetta G, Rosà R, Merler S. First outbreak of Zika virus in the continental United States: a modelling analysis. Eurosurveillance. 2017 Sep 14;22(37).* Marini G, Guzzetta G, Baldacchino F, Arnoldi D, Montarsi F, Capelli G, Rizzoli A, Merler S, Rosà R. The effect of interspecific competition on the temporal dynamics of Aedes albopictus and Culex pipiens. Parasites & vectors. 2017 Dec;10(1):102.

Full Text: PDF