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Multivariate Regression Tree is a tree where univariate response variable has been substituted by a multivariate response variable. It has been proposed to investigate complex ecological data. We apply the Multivariate Regression Tree to investigate social and economical issues in order to comprehend if this method can be generalized and used in different research fields. We apply the Multivariate Regression Tree to identify the causes of death in Italian Counties in 2019. The first results evidence the capacity of Multivariate Regression Tree to define nodes characterized for specific causes of death and to classify together geographical areas with similar impact levels of the variables.